iPS Cell Reprogramming Technology - A Method For Producing Patient-Specific Cancer Stem Cells
As previously stated, cancer stem cells are responsible for cancer drug resistance, recurrence and metastasis. Studies have shown that induced pluripotent stem cell (iPSC) reprogramming can transform cancer cells back into a cancer stem cell state. This phenomena provides an ability to create large supplies of personalized cancer stem cells. Creating large numbers of cancer stem cells allows the potential for performing drug testing of a patient's cancer stem cell with available cancer drugs and the development of new drugs.